Recombinant Human SOST (C-6His)

Name: Recombinant Human SOST (C-6His)
SKU: RP00032

Cat.No. : RP00032 Tag: C-6His

Expressed Region: Gln24-Tyr213 Expression System: Human Cell

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Product Details

Target Information

Cat. No.	RP00032
Description	The Recombinant Human SOST (C-6His) is produced in our Human Cell expression system. The amino acid region expressed is Gln24-Tyr213 with a 6His tag at the C terminus.
Species	Human
Tag	C-6His
Mol. Weight	22.3 KDa
Expressed Region	Gln24-Tyr213
Expression System	Human Cell
Format	Powder
Formulation	Lyophilized from a 0.2 μm filtered solution of 20mM NaAc-Hac, 8% Trehalose, 0.02% Tween 80, pH5.0.
Conjugate	Unconjugated
Endotoxin Level	< 1 EU/µg of protein by LAL method
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	SOST
Background	Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease.
Synonyms	Sclerostin;SOST; UNQ2976; PRO7455; PRO7476

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