Transfected Stable Cell Lines
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Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CDFR012354
| Cat. No. | CDFR012354 |
| Description | NativeORF clone of Rattus norvegicus sclerosteosis (Sost) as transfection-ready DNA NM_030584.1 |
| Product Type | cDAN Clone |
| Gene Abbr | Sost |
| Species | Rat |
| Target Gene | SOST |
| Background | Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease. [provided by RefSeq, Jul 2008] |
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