Recombinant Human IL-6 (Tag free)

Name: Recombinant Human IL-6 (Tag free)
SKU: RP00358
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00358 Tag : Tag free

Expressed Region : Val30-Met212 Expression System : E.coli

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Product Information

Gene Information

Cat. No.	RP00358
Description	The Recombinant Human IL-6 is produced in our E.coli expression system. The amino acid region expressed is Val30-Met212 without tag.
Species	Human
Tag	Tag free
Mol Weight	20.9 KDa
Conjugate	Unconjugated
Format	Powder
Expressed Region	Val30-Met212
Expression System	E.coli
Formulation	Lyophilized from a 0.2 μm filtered solution of 20mM PB, 5% Sucorse, 4% Mannitol, 0.05% PS-80, pH7.4.
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Endotoxin Level	< 0.01 EU/µg of protein by LAL method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	IL6
Synonyms	Interleukin-6; IL-6; B-Cell Stimulatory Factor 2; BSF-2; CTL Differentiation Factor; CDF; Hybridoma Growth Factor; Interferon Beta-2; IFN-Beta-2; IL6; IFNB2

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This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Elevated levels of the encoded protein have been found in virus infections, including COVID-19 (disease caused by SARS-CoV-2).

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