Rat IL6 ORF clone(NM_012589.1)

Name: Rat IL6 ORF clone(NM_012589.1)
SKU: CDCL184902
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCL184902

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Product Information

Gene Information

Cat. No.	CDCL184902
Description	ORF Clone of Rattus norvegicus interleukin 6 DNA.
Product Type	ORF clone
Gene Abbr	IL6
Species	Rat
ORF Size	636bp
Vector	pMD18-T
Warning	This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Storage	store at -20°C

Target Gene

IL6

Background

This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Elevated levels of the encoded protein have been found in virus infections, including COVID-19 (disease caused by SARS-CoV-2). [provided by RefSeq, Aug 2020]

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