Recombinant Human GPNMB (C-6His)

Name: Recombinant Human GPNMB (C-6His)
SKU: RP00178
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00178 Tag : C-6His

Expressed Region : Lys23-Pro486 Expression System : Human Cell

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Product Information

Gene Information

Cat. No.	RP00178
Description	The Recombinant Human GPNMB (C-6His) is produced in our Human Cell expression system. The amino acid region expressed is Lys23-Pro486 with a 6His tag at the C terminus.
Species	Human
Tag	C-6His
Mol Weight	53.09 KDa
Conjugate	Unconjugated
Format	Powder
Expressed Region	Lys23-Pro486
Expression System	Human Cell
Formulation	Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Endotoxin Level	< 1 EU/µg of protein by LAL method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	GPNMB
Background	The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.
Synonyms	Transmembrane Glycoprotein NMB; Transmembrane Glycoprotein HGFIN; GPNMB; HGFIN; NMB

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