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Rat Gpnmb ORF Clone(NM_133298.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR381007

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Product Information

Gene Information

Cat. No. CDCR381007
Product Type ORF Clone
Gene Abbr Gpnmb
Species Rat
Tag C-terminal Myc-DDK
ORF Size 1719 bp
Vector pCMV6-Entry
Target Gene GPNMB
Background The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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