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Recombinant Human CLDN6 (VLP)

For research use only. Not intended for any clinical use.

Cat. No. :   RP00564 Tag :   C-Flag

Expressed Region :   Met1-Val220 Expression System :   Human Cell

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Product Information

Gene Information

Cat. No. RP00564
Description Recombinant Human CLDN6 (VLP) is produced in our Human Cell expression system. The amino acid region expressed is Met1-Val220 with a Flag tag at the C terminus.
Species Human
Tag C-Flag
Mol Weight 41.8 KDa
Format Liquid
Expressed Region Met1-Val220
Expression System Human Cell
Formulation Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
Purity >95% as determined by SDS-PAGE.
>90% as determined by SEC-MALS.
Endotoxin Level < 1 EU/µg of protein by LAL method
Storage Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Target Gene CLDN6
Synonyms Claudin-6; Claudin6; Claudin 6; CLDN6; CLDN-6;CLDN 6;Skullin; UNQ757/PRO1488
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Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.

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