Rat Cldn6 cDNA Clone(NM_001102364.1)

Name: Rat Cldn6 cDNA Clone(NM_001102364.1)
SKU: CDFR005456
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR005456

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Product Information

Gene Information

Cat. No.	CDFR005456
Description	NativeORF clone of Rattus norvegicus claudin 6 (Cldn6) as transfection-ready DNA NM_001102364.1
Product Type	cDAN Clone
Gene Abbr	Cldn6
Species	Rat
Size	10 ug
Vector	pCMV6Entry

Target Gene

CLDN6

Background

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.[provided by RefSeq, Aug 2010]

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