Recombinant Human BIRC5 (Tag free)

Name: Recombinant Human BIRC5 (Tag free)
SKU: RP00251
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00251 Tag : Tag free

Expressed Region : Met1-Asp142 Expression System : E.coli

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Product Information

Gene Information

Cat. No.	RP00251
Description	The Recombinant Human BIRC5 is produced in our E.coli expression system. The amino acid region expressed is Met1-Asp142 without tag.
Species	Human
Tag	Tag free
Mol Weight	16.4 KDa
Conjugate	Unconjugated
Format	Powder
Expressed Region	Met1-Asp142
Expression System	E.coli
Formulation	Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, pH 7.5.
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Endotoxin Level	< 1 EU/µg of protein by LAL method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	BIRC5
Background	This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Synonyms	Baculoviral IAP Repeat-Containing Protein 5; Apoptosis Inhibitor 4; Apoptosis Inhibitor Survivin; BIRC5; API4; IAP4

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