Human BIRC5 adenoviral particles

Name: Human BIRC5 adenoviral particles
SKU: AD01831Z
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : AD01831Z

Storage : -80℃ Shipping : Frozen on dry ice

Titer: Size:

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Virus Particles Information

Quality Control

Gene Information

Cat. No.	AD01831Z
Description	Adenovirus with ORF of baculoviral IAP repeat containing 5 (BIRC5), transcript variant 1.
Gene	BIRC5
Species	Human
Titer	Varies lot by lot, for example, ≥1x10^10 IFU/mL, ≥1x10^11 IFU/mL, ≥1x10^11 VP/mL etc.
Size	Varies lot by lot, for example, 100 ul, 500 ul, 1 mL etc.
Storage	Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping	Frozen on dry ice

Summary	Creative Biogene ensures high-quality adenovirus particles by optimizing and standardizing production protocols and performing stringent quality control (QC). The specific QC experiments performed vary between adenovirus particle lots.
Endotoxin	Endotoxins, primarily derived from Gram-negative bacteria, can trigger adverse immune responses. Endotoxin contamination is a significant concern in adenovirus production, especially for applications in animal studies and gene therapy. Creative Biogene utilizes rigorous endotoxin detection methods to monitor the endotoxin level in our produced adenovirus particles to ensure regulatory compliance.
Sterility	Creative Biogene ensures that adenovirus products are free of any bacterial, fungal and other microbial contamination.
Ad5 E1 Detection	All Creative Biogene adenoviruses are PCR tested to ensure that there are no detectable E1 sequences in the particles, which could be from revertants or external E1 contamination.
RCA Assays	Adenovirus products originating at Creative Biogene are guaranteed to have undetectable replication-competent adenovirus (RCA). This quality control measure is important because there is always the possibility of wild-type contamination due to revertants or environmental sources.
PFU Titering	All purified adenovirus preparations are tested for infectious titer. Creative Biogene's PFU test takes a few days longer but counts true plaques in HEK cells rather than estimating PFU titers via IHC staining or TCI50 of infected cells.

Gene Name	BIRC5 baculoviral IAP repeat containing 5 [ Homo sapiens ]
Gene Symbol	BIRC5
Synonyms	API4; EPR-1
Gene Description	baculoviral IAP repeat-containing 5 (survivin)
GeneID	332
Uni ProtID	H3BLT4
mRNA Refseq	NM_001012271.1
Protein Refseq	NP_001012271.1
Chromosome Location	17q25
Function	Ran GTPase binding; chaperone binding; cobalt ion binding; cofactor binding; cysteine-type endopeptidase inhibitor activity; cysteine-type endopeptidase inhibitor activity involved in apoptotic process; enzyme binding; identical protein binding; metal ion binding; microtubule binding; microtubule binding; protein binding; protein heterodimerization activity; protein homodimerization activity; protein homodimerization activity; tubulin binding; zinc ion binding; zinc ion binding;
Pathway	Apoptosis, organism-specific biosystem; Apoptosis Modulation and Signaling, organism-specific biosystem; Aurora A signaling, organism-specific biosystem; Aurora B signaling, organism-specific biosystem; Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; Colorectal cancer, organism-specific biosystem;
MIM	603352

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