Recombinant Human ANGPT1 (N-Fc)

Name: Recombinant Human ANGPT1 (N-Fc)
SKU: RP00599
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00599 Tag : N-Fc

Expressed Region : Asp256-Phe498 Expression System : Human Cell

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Product Information

Gene Information

Cat. No.	RP00599
Description	Recombinant Human ANGPT1 (N-Fc) is produced in our Human Cell expression system. The amino acid region expressed is Asp256-Phe498 with a Fc tag at the N terminus.
Species	Human
Tag	N-Fc
Mol Weight	53.9 KDa
Conjugate	Unconjugated
Format	Powder
Expressed Region	Asp256-Phe498
Expression System	Human Cell
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Endotoxin Level	< 1 EU/µg of protein by LAL method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	ANGPT1
Synonyms	AGP1; AGPT; Ang1; ANG-1; angiopoietin 1; Angiopoietin-1; ANGPT1

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This gene encodes a secreted glycoprotein that belongs to the angiopoietin family. Members of this family play important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Mutations in this gene are associated with hereditary angioedema.

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