Recombinant Cynomolgus AXL (C-Fc)

Name: Recombinant Cynomolgus AXL (C-Fc)
SKU: RP00084

Cat.No. : RP00084 Tag: C-Fc

Expressed Region: Pro27-Pro293 Expression System: Human Cell

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Product Details

Target Information

Cat. No.	RP00084
Description	The Recombinant Cynomolgus AXL (C-Fc) is produced in our Human Cell expression system. The amino acid region expressed is Pro27-Pro293 with a Fc tag at the C terminus.
Species	Cynomolgus
Tag	C-Fc
Mol. Weight	55.8 KDa
Expressed Region	Pro27-Pro293
Expression System	Human Cell
Format	Powder
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Endotoxin Level	< 1 EU/µg of protein by LAL method
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	AXL
Background	The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. The encoded protein acts as a host cell receptor for multiple viruses, including Marburg, Ebola and Lassa viruses and is a candidate receptor for the SARS-CoV2 virus.
Synonyms	Tyrosine-protein kinase receptor UFO; AXL oncogene; UFO

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