Recombinant Cynomolgus AXL (C-Fc)

Name: Recombinant Cynomolgus AXL (C-Fc)
SKU: RP00084
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00084 Tag : C-Fc

Expressed Region : Pro27-Pro293 Expression System : Human Cell

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Product Information

Gene Information

Cat. No.	RP00084
Description	The Recombinant Cynomolgus AXL (C-Fc) is produced in our Human Cell expression system. The amino acid region expressed is Pro27-Pro293 with a Fc tag at the C terminus.
Species	Cynomolgus
Tag	C-Fc
Mol Weight	55.8 KDa
Format	Powder
Expressed Region	Pro27-Pro293
Expression System	Human Cell
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Endotoxin Level	< 1 EU/µg of protein by LAL method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	AXL
Synonyms	Tyrosine-protein kinase receptor UFO; AXL oncogene; UFO

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The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. The encoded protein acts as a host cell receptor for multiple viruses, including Marburg, Ebola and Lassa viruses and is a candidate receptor for the SARS-CoV2 virus.

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