Rat Axl cDNA Clone(NM_031794.1)

Name: Rat Axl cDNA Clone(NM_031794.1)
SKU: CDFR012924
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR012924

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Product Information

Gene Information

Cat. No.	CDFR012924
Description	NativeORF clone of Rattus norvegicus Axl receptor tyrosine kinase (Axl), transcript variant 1 as transfection-ready DNA NM_031794.1
Product Type	cDAN Clone
Gene Abbr	Axl
Species	Rat
Vector	pCMV6Entry

Target Gene

AXL

Background

The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. The encoded protein acts as a host cell receptor for multiple viruses, including Marburg, Ebola and Lassa viruses and is a candidate receptor for the SARS-CoV2 virus. [provided by RefSeq, Sep 2021]

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