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Mouse Axl ORF clone (NM_001190975.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR032600

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Product Information

Gene Information

Cat. No. CDCR032600
Description Mus musculus AXL receptor tyrosine kinase (Axl), transcript variant 3, mRNA.
Product Type ORF clone
Gene Abbr Axl
Species Mouse
ORF Size 2376
Format purified plasmid
Vector pDONR
Target Gene AXL
Background The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. The encoded protein acts as a host cell receptor for multiple viruses, including Marburg, Ebola and Lassa viruses and is a candidate receptor for the SARS-CoV2 virus. [provided by RefSeq, Sep 2021]
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