Transfected Stable Cell Lines
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Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CDCR032600
| Cat. No. | CDCR032600 |
| Description | Mus musculus AXL receptor tyrosine kinase (Axl), transcript variant 3, mRNA. |
| Product Type | ORF clone |
| Gene Abbr | Axl |
| Species | Mouse |
| ORF Size | 2376 |
| Format | purified plasmid |
| Vector | pDONR |
| Target Gene | AXL |
| Background | The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. The encoded protein acts as a host cell receptor for multiple viruses, including Marburg, Ebola and Lassa viruses and is a candidate receptor for the SARS-CoV2 virus. [provided by RefSeq, Sep 2021] |
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