Transfected Stable Cell Lines
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Cat. No. : RP00546 Tag : C-Avi-6His
Expressed Region : Leu24-Gln186 Expression System : Human Cell
| Cat. No. | RP00546 |
| Description | Biotinylated Human TNFRSF9 (C-Avi-6His) is produced in our Human Cell expression system. The amino acid region expressed is Leu24-Gln186 with a Avi-6His tag at the C terminus. |
| Species | Human |
| Tag | C-Avi-6His |
| Mol Weight | 19.9 KDa |
| Conjugate | Unconjugated |
| Format | Powder |
| Expressed Region | Leu24-Gln186 |
| Expression System | Human Cell |
| Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| Purity |
>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS. |
| Endotoxin Level | < 1 EU/µg of protein by LAL method |
| Storage | Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles. |
| Shipping | The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below. |
| Reconstitution | Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Target Gene | TNFRSF9 |
| Background | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. |
| Synonyms | CD137; ILA; TNFRSF9; 4-1BB ligand receptor; CDw137; T-cell antigen 4-1BB homolog; T-cell antigen ILA |
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