Biotinylated Human DKK-1 (C-Avi-6His)

Name: Biotinylated Human DKK-1 (C-Avi-6His)
SKU: RP00428
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00428 Tag : C-Avi-6His

Expressed Region : Thr32-His266 Expression System : Human Cell

Inquire for Price

Product Information

Gene Information

Cat. No.	RP00428
Description	The Biotinylated Human DKK-1 (C-Avi-6His) is produced in our Human Cell expression system. The amino acid region expressed is Thr32-His266 with a Avi-6His tag at the C terminus.
Species	Human
Tag	C-Avi-6His
Mol Weight	28.4 KDa
Conjugate	Biotinylated
Format	Powder
Expressed Region	Thr32-His266
Expression System	Human Cell
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Endotoxin Level	< 1 EU/µg of protein by LAL method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	DKK1
Background	This gene encodes a member of the dickkopf family of proteins. Members of this family are secreted proteins characterized by two cysteine-rich domains that mediate protein-protein interactions. The encoded protein binds to the LRP6 co-receptor and inhibits beta-catenin-dependent Wnt signaling. This gene plays a role in embryonic development and may be important in bone formation in adults. Elevated expression of this gene has been observed in numerous human cancers and this protein may promote proliferation, invasion and growth in cancer cell lines.
Synonyms	Dickkopf-related protein 1; Dickkopf-1; Dkk-1

Quick Inquiry

Q & A

Customer Reviews

Ask a Question

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

Question *

Name

Country *

Email *

Write a Review

Write a review of your use of Biogene products and services in your research. Your review can help your fellow researchers make informed purchasing decisions.

Product Name *

Catalog Name *

Rating

Needs improvement

Satisfaction

General satisfaction

Very satisfaction

Product Review Title *

Summary *