Recombinant Human DKK-1 (N-8His)

Name: Recombinant Human DKK-1 (N-8His)
SKU: RP00341
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00341 Tag : N-8His

Expressed Region : Thr32-His266 Expression System : Human Cell

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Product Information

Gene Information

Cat. No.	RP00341
Description	The Recombinant Human DKK-1 (N-8His) is produced in our Human Cell expression system. The amino acid region expressed is Thr32-His266 with a 8His tag at the N terminus.
Species	Human
Tag	N-8His
Mol Weight	27 KDa
Conjugate	Unconjugated
Format	Powder
Expressed Region	Thr32-His266
Expression System	Human Cell
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Endotoxin Level	< 0.01 EU/µg of protein by LAL method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	DKK1
Background	This gene encodes a member of the dickkopf family of proteins. Members of this family are secreted proteins characterized by two cysteine-rich domains that mediate protein-protein interactions. The encoded protein binds to the LRP6 co-receptor and inhibits beta-catenin-dependent Wnt signaling. This gene plays a role in embryonic development and may be important in bone formation in adults. Elevated expression of this gene has been observed in numerous human cancers and this protein may promote proliferation, invasion and growth in cancer cell lines.
Synonyms	Dickkopf-related protein 1;Dickkopf-1;Dkk-1

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