Transfected Stable Cell Lines
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Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : VAR-024
| Cat. No. | VAR-024 |
| Description | Poly (I:C), a synthetic double-stranded RNA (dsRNA) analog, is known to interact with toll-like receptor 3 (TLR3). Poly (I:C) can activate the nuclear transcription factor NF-kB as well as stimulate the production of type I interferons (IFNs) leading to cytokine secretion. It is a common tool for scientific research on the immune system. |
| Product Type | Toll-like Receptor Agonists |
| Alias | Polyinosinic-polycytidylic acid |
| Storage | Store at -20°C |
A: This is because Poly(I:C) can activate the transcription factor NF-kB, and stimulate the production of type I interferons (IFNs), which leads to cytokine secretion.
A: No, that's not the case. There are certain concentration and dosage requirements for using this product. Appropriate doses can enhance immune activity, while larger doses can lead to inhibitory effects.
A: Poly(I:C) is an analog of synthetic double-stranded RNA (dsRNA), so anti-dsRNA antibodies can be used to detect its content and distribution.
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We have successfully studied the effects of different doses of Poly I:C on immune cell activity and cytokines.
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