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GSK2245035

For research use only. Not intended for any clinical use.
Cat.No.
VAR-045
Description
GSK2245035 is a selective Toll-like receptor 7 (TLR7) agonist with preferential Type-1 interferon (IFN)-stimulating properties. GSK2245035 displays extraordinary IFNα inducing potency and IFNα/TNFα selectivity.
Product Type
Toll-like Receptor Agonists
Purity
≥98%
Storage
Store at -20°C in powder form. Store at -80°C once reconstituted.

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Customer Q&As
What is the function of GSK2245035?

A: GSK2245035 effectively inhibits allergen-induced Th2 cell cytokine production in human peripheral blood cell cultures.

What is the solubility of GSK2245035?

A: Solubility in DMSO: 125 mg/mL (320.09 mM; Requires ultrasonic).

If precipitation or phase separation occurs during preparation, how should it be handled?

A: GSK2245035 can be facilitated in dissolution through heating and/or sonication.

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