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Cat.No. : CSC-BS0005 Host Cell: CHO-K1
| Cat. No. | CSC-BS0005 |
| Description | This cell line is engineered to stably produce Pembrolizumab which is a monoclonal antibody against human PDCD1/PD1. |
| Biosimilar | Pembrolizumab |
| Host Cell | CHO-K1 |
| Host Cell Species | Cricetulus griseus (Chinese hamster) |
| Stability | Validated for at least 10 passages |
| Application | 1. Biosimilar Development 2. Large-Scale Biomanufacturing 3. Preclinical Research 4. Drug Development and Testing |
| Growth Conditions | 37° C, 5% CO2 |
| Quality Control | Negative for bacteria, yeast, fungi and mycoplasma. |
| Shipping | Dry ice |
| Storage | Liquid nitrogen |
| Mycoplasma | Negative |
| Format | One frozen vial containing millions of cells |
| Storage | Liquid nitrogen |
| Safety Considerations |
The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach. |
| Ship | Dry ice |
A: Pembrolizumab is an antibody-based medicine that is used to treat different types of cancer.
A: Pembrolizumab works by targeting and blocking a protein called PD-1, which is found on the surface of some immune cells. This protein helps prevent the immune system from attacking healthy cells in the body. However, tumors can also use PD-1 to trick the immune system into thinking they are normal cells. Pembrolizumab stops this from happening, enabling the immune system to better recognize and attack cancer cells.
A: Pembrolizumab is a humanized antibody used in cancer immunotherapy that treats melanoma, lung cancer, head and neck cancer, cervical cancer, Hodgkin lymphoma, stomach cancer, and certain types of breast cancer.
A: Pembrolizumab is a selectively humanized IgG4 kappa monoclonal antibody that inhibits the programmed death-1 (PD-1) receptor, a component of immune checkpoint regulation in the tumor microenvironment.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
That's great. The stable cell line ensures consistency in the production of the Pembrolizumab.
United States
01/27/2022
To produce a therapeutic dose of pembrolizumab, a stable cell line is needed. Creative Biogene's stable cell line is a good choice.
United States
07/19/2022
The stable cell line can ensure continuous production of the Pembrolizumab. This helps a lot with my project.
United States
11/03/2022
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