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Cat.No. : CSC-BS0003 Host Cell: CHO-K1
| Cat. No. | CSC-BS0003 |
| Description | This cell line is engineered to stably produce Cetuximab which is a monoclonal antibody against human EGFR. |
| Biosimilar | Cetuximab |
| Host Cell | CHO-K1 |
| Host Cell Species | Cricetulus griseus (Chinese hamster) |
| Stability | Validated for at least 10 passages |
| Application | 1. Biosimilar Development 2. Large-Scale Biomanufacturing 3. Preclinical Research 4. Drug Development and Testing |
| Growth Conditions | 37° C, 5% CO2 |
| Quality Control | Negative for bacteria, yeast, fungi and mycoplasma. |
| Shipping | Dry ice |
| Storage | Liquid nitrogen |
| Mycoplasma | Negative |
| Format | One frozen vial containing millions of cells |
| Storage | Liquid nitrogen |
| Safety Considerations |
The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach. |
| Ship | Dry ice |
A: Cetuximab is a monoclonal antibody drug that is used in the treatment of cancer. It works by preventing the cancer cells from multiplying and spreading in the body.
A: Cetuximab is specifically designed to target a protein called epidermal growth factor receptor (EGFR), which is often found on the surface of cancer cells. By blocking this receptor, the drug prevents the cancer cells from receiving the signal to divide and grow.
A: Cetuximab is used to treat several types of cancer, including head and neck cancer and colorectal cancer.
A: CHO-K1 cells are a type of Chinese hamster ovary cell that has been adapted for use in industrial biotechnology. These cells are particularly useful for producing recombinant proteins and monoclonal antibodies like cetuximab.
A: The anti-epidermal growth factor receptor (EGFR) monoclonal antibody cetuximab specifically binds EGFR with high affinity, blocking growth factor binding, receptor activation, and subsequent signaling events leading to cell proliferation.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
Cetuximab Stable Cell Lines can be used in industrial scale-up processes since they can be easily adapted to bioreactor systems and can produce high quantities of the desired product.
United States
02/23/2023
Great! Cetuximab Stable Cell Line has been genetically modified to ensure they grow and differentiate properly in culture, and can produce high levels of the desired protein.
United States
04/11/2023
The ability of the cetuximab cell to grow and divide quickly saved me a lot of time. I recommend it.
United States
08/23/2020
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