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Adalimumab Stable Cell Line - CHO-K1

For research use only. Not intended for any clinical use.

Cat. No. :   CSC-BS0006

Host Cell :   CHO-K1 Size :   >1x106 frozen cells/vial

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Cell Line Information

Cell Culture Information

Safety and Packaging

Cat. No. CSC-BS0006
Description This cell line is engineered to stably produce Adalimumab which is a monoclonal antibody against human TNF.
Target Gene Adalimumab
Host Cell CHO-K1
Host Cell Species Cricetulus griseus (Chinese hamster)
Applications

1. Biosimilar Development

2. Large-Scale Biomanufacturing

3. Preclinical Research

4. Drug Development and Testing

Size >1x106 frozen cells/vial
Stability Validated for at least 10 passages
Quality Control Negative for bacteria, yeast, fungi and mycoplasma.
Growth Conditions 37° C, 5% CO2
Storage Liquid nitrogen
Shipping Dry ice
Revival Rapidly thaw cells in a 37°C water bath. Transfer contents into a tube containing pre-warmed media. Centrifuge cells and seed into a 25 cm2 flask containing pre-warmed media.
Mycoplasma Negative
Format One frozen vial containing millions of cells
Storage Liquid nitrogen
Safety Considerations The following safety precautions should be observed.
1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum.
2. No eating, drinking or smoking while handling the stable line.
3. Wash hands after handling the stable line and before leaving the lab.
4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells.
5. All waste should be considered hazardous.
6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship Dry ice
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Q & A

Customer Reviews

Customer Q&As
What is Adalimumab?

A: Adalimumab is a disease-modifying antirheumatic drug (DMARD) and monoclonal antibody that works by inactivating tumor necrosis factor-alpha (TNFα).

What is the mechanism of action of Adalimumab?

A: Adalimumab works by selectively binding to a protein called tumor necrosis factor-alpha (TNF-α). By binding to TNF-α, adalimumab inhibits its activity and reduces inflammation.

What type of cancer is Adalimumab used for?

A: Pembrolizumab has shown promising results in treating many types of cancer, including melanoma, non-small cell lung cancer, and bladder cancer.

Is Adalimumab a PD-1 TNF-α?

A: Yes. Adalimumab is a specific inhibitor of TNF-α, and does not affect other cytokines or immune cells. This makes it a targeted therapy with fewer side effects compared to non-specific immunosuppressive drugs that affect multiple pathways.

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Customer Reviews
Great!

Great! To produce a therapeutic dose of Adalimumab, a stable cell line is needed.

United States

Save time

The adalimumab stable cells are grown in suspension culture, which not only simplifies the purification process but also reduces the risk of contamination. I recommend it.

United States

Effective

The stable cell line that produces functional pembrolizumab using CHO-K1 cells is a significant step forward in the fight against cancer. This helps a lot with my project.

Germany

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