Humanized TNFRSF14 Murine Tumor Cell Line

Name: Humanized TNFRSF14 Murine Tumor Cell Line
SKU: CSC-RH0092M
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-RH0092M Size : >1x10⁶ frozen cells/vial

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Cell Line Information

Safety and Packaging

Gene Information

Cat. No.	CSC-RH0092M
Description	These transgenic cells carry humanized TNFRSF14 and form solid tumors in vivo. The endogenous mouse Tnfrsf14 gene was replaced by human TNFRSF14 gene.
Target Gene	TNFRSF14
Alias	ATAR, CD270, HVEA, HVEM, LIGHTR, TR2
Size	>1x10⁶ frozen cells/vial
Storage	Liquid nitrogen
Shipping	Dry ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	TNFRSF14 tumor necrosis factor receptor superfamily, member 14 [ Homo sapiens ]
Gene Symbol	TNFRSF14
Synonyms	TR2; ATAR; HVEA; HVEM; CD270; LIGHTR
Gene Description	tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)
Gene ID	8764
Uni Prot ID	Q92956
m RNA Refseq	NM_003820.2
Protein Refseq	NP_003811.2
Chromosome Location	1p36.32
Function	protein binding; tumor necrosis factor-activated receptor activity; ubiquitin protein ligase binding;
Pathway	Adaptive Immune System, organism-specific biosystem; Costimulation by the CD28 family, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Herpes simplex infection, organism-specific biosystem; Herpes simplex infection, conserved biosystem; Immune System, organism-specific biosystem;
MIM	602746

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