Pages
Products

Human TLR2 mRNA

For research use only. Not intended for any clinical use.
Cat.No.
PMRN-0268
Description
The TLR2 mRNA encodes the human toll like receptor 2 (TLR2) protein, a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLR2 is thought to promote apoptosis in response to bacterial lipoproteins.
Alias
CD282, TIL4
Features
• mRNA synthesized on error free sequence verified plasmid DNA template
• 100% replacement of UTP with modified nucleotides 5-Methoxy-UTP
• Cap 1 Capping and poly-A tailed incorporated
• Degrades the DNA template after RNA synthesis with DNase
Sequence
MPHTLWMVWV LGVIISLSKE ESSNQASLSC DRNGICKGSS GSLNSIPSGL TEAVKSLDLS NNRITYISNS DLQRCVNLQA LVLTSNGINT IEEDSFSSLG SLEHLDLSYN YLSNLSSSWF KPLSSLTFLN LLGNPYKTLG ETSLFSHLTK LQILRVGNMD TFTKIQRKDF AGLTFLEELE IDASDLQSYE PKSLKSIQNV SHLILHMKQH ILLLEIFVDV TSSVECLELR DTDLDTFHFS ELSTGETNSL IKKFTFRNVK ITDESLFQVM KLLNQISGLL ELEFDDCTLN GVGNFRASDN DRVIDPGKVE TLTIRRLHIP RFYLFYDLST LYSLTERVKR ITVENSKVFL VPCLLSQHLK SLEYLDLSEN LMVEEYLKNS ACEDAWPSLQ TLILRQNHLA SLEKTGETLL TLKNLTNIDI SKNSFHSMPE TCQWPEKMKY LNLSSTRIHS VTGCIPKTLE ILDVSNNNLN LFSLNLPQLK ELYISRNKLM TLPDASLLPM LLVLKISRNA ITTFSKEQLD SFHTLKTLEA GGNNFICSCE FLSFTQEQQA LAKVLIDWPA NYLCDSPSHV RGQQVQDVRL SVSECHRTAL VSGMCCALFL LILLTGVLCH RFHGLWYMKM MWAWLQAKRK PRKAPSRNIC YDAFVSYSER DAYWVENLMV QELENFNPPF KLCLHKRDFI PGKWIIDNII DSIEKSHKTV FVLSENFVKS EWCKYELDFS HFRLFDENND AAILILLEPI EKKAIPQRFC KLRKIMNTKT YLEWPMDEAQ REGFWVNLRA AIKS
Species
Homo sapiens (Human)
Storage
Store at or below -70°C. Avoid repeated freeze/thaw cycles. Aliquot if necessary using RNase-free equipment, reagents, pipet tips, tubes, and containers.

Publications

Q & A

Customer Reviews

Customer Q&As
What is Human TLR2 mRNA?

A: Human TLR2 mRNA is the messenger RNA for the human Toll-like receptor 2 (Toll-likereceptor2) gene, which encodes an important immune receptor involved in the immune response of the human immune system.

What is the function of Human TLR2 mRNA?

A: The protein encoded by Human TLR2 mRNA is a receptor that recognizes and binds to microbial molecular patterns (PAMPs) such as bacteria, fungi, and viruses to initiate an immune response. It plays an important role in inflammatory responses, antibacterial and antiviral immunity.

What is the regulatory mechanism of Human TLR2 mRNA?

A: Human TLR2 mRNA expression is affected by a variety of regulatory mechanisms, including transcription factor binding, DNA methylation and histone modification. These regulatory mechanisms can modulate the expression level of TLR2 according to different stimuli and environmental conditions.

Are there drugs that can regulate Human TLR2 mRNA expression?

A: There are no specific drugs that directly regulate Human TLR2 mRNA expression. However, several studies are exploring the regulation of TLR2 function by modulating other molecules in the TLR2 signaling pathway for the treatment of infections and immune-related diseases.

What is the mechanism of action of HumanTLR2 mRNA in the immune response?

A: Human TLR2 mRNA encodes a protein that recognizes and binds to microbial molecular patterns, thereby activating the immune response.Activation of TLR2 triggers a series of signaling pathways, including pathways such as nuclear factor-κB (NF-κB) and mitogen-activated protein kinase (MAPK), which ultimately lead to inflammatory responses and activation of immune cells.

Ask a Question

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

Customer Reviews
Rapid & Simple

Can quickly and simply participate in the expression of immune metabolism.

Germany

07/19/2022

Write a Review

Write a review of your use of Biogene products and services in your research. Your review can help your fellow researchers make informed purchasing decisions.

Needs improvement

Satisfaction

General satisfaction

Very satisfaction

CBpromise

Our promise to you:
Guaranteed product quality, expert customer support.

24x7 CUSTOMER SERVICE
CONTACT US TO ORDER
Quick Inquiry

Inquiry