Human FGFR2 mRNA

Name: Human FGFR2 mRNA
SKU: PMRN-0108
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : PMRN-0108

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Product Information

Cat. No.	PMRN-0108
Description	The FGFR2 mRNA encodes the human fibroblast growth factor receptor 2 (FGFR2) protein, a member of the fibroblast growth factor receptor (FGFR) family. The extracellular portion of FGFR2 protein can interact with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation.
Gene Type	Other
RNA Type	mRNA
Gene Name	FGFR2
Species	Homo sapiens (Human)
Alias	BBDS, BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25
Features	• mRNA synthesized on error free sequence verified plasmid DNA template • 100% replacement of UTP with modified nucleotides 5-Methoxy-UTP • Cap 1 Capping and poly-A tailed incorporated • Degrades the DNA template after RNA synthesis with DNase
Sequence	MVSWGRFICL VVVTMATLSL ARPSFSLVED TTLEPEEPPT KYQISQPEVY VAAPGESLEV RCLLKDAAVI SWTKDGVHLG PNNRTVLIGE YLQIKGATPR DSGLYACTAS RTVDSETWYF MVNVTDAISS GDDEDDTDGA EDFVSENSNN KRAPYWTNTE KMEKRLHAVP AANTVKFRCP AGGNPMPTMR WLKNGKEFKQ EHRIGGYKVR NQHWSLIMES VVPSDKGNYT CVVENEYGSI NHTYHLDVVE RSPHRPILQA GLPANASTVV GGDVEFVCKV YSDAQPHIQW IKHVEKNGSK YGPDGLPYLK VLKAAGVNTT DKEIEVLYIR NVTFEDAGEY TCLAGNSIGI SFHSAWLTVL PAPGREKEIT ASPDYLEIAI YCIGVFLIAC MVVTVILCRM KNTTKKPDFS SQPAVHKLTK RIPLRRQVTV SAESSSSMNS NTPLVRITTR LSSTADTPML AGVSEYELPE DPKWEFPRDK LTLGKPLGEG CFGQVVMAEA VGIDKDKPKE AVTVAVKMLK DDATEKDLSD LVSEMEMMKM IGKHKNIINL LGACTQDGPL YVIVEYASKG NLREYLRARR PPGMEYSYDI NRVPEEQMTF KDLVSCTYQL ARGMEYLASQ KCIHRDLAAR NVLVTENNVM KIADFGLARD INNIDYYKKT TNGRLPVKWM APEALFDRVY THQSDVWSFG VLMWEIFTLG GSPYPGIPVE ELFKLLKEGH RMDKPANCTN ELYMMMRDCW HAVPSQRPTF KQLVEDLDRI LTLTTNEEYL DLSQPLEQYS PSYPDTRSSC SSGDDSVFSP DPMPYEPCLP QYPHINGSVK T
Storage	Store at or below -70°C. Avoid repeated freeze/thaw cycles. Aliquot if necessary using RNase-free equipment, reagents, pipet tips, tubes, and containers.

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What is Human FGFR2 mRNA?

A: Human FGFR2 mRNA is a human gene encoded mRNA derived from the fibroblast growth factor receptor 2 (FGFR2) gene.

What is the FGFR2 gene?

A: The FGFR2 gene is a human gene that encodes a fibroblast growth factor receptor that participates in biological processes such as cell proliferation, differentiation, and migration. The abnormal expression of this gene may be related to various diseases.

How to regulate the expression of Human FGFR2 mRNA?

A: Regulating mRNA expression can be achieved through various methods, including but not limited to: using small molecule inhibitors or activators, regulating transcription factors or microRNAs, etc. However, specific methods still need to be determined based on specific genes and diseases. There is currently no specific regulatory method widely accepted and applied for Human FGFR2 mRNA.

What are the types of mutations in the Human FGFR2 gene?

A: The types of mutations in the FGFR2 gene include point mutations, insertions/deletions, rearrangements, etc. Among them, some mutations may cause changes in the structure and function of FGFR2 protein, thereby affecting biological processes such as cell proliferation, differentiation, and migration. These mutations may be related to the occurrence and development of cancer, cardiovascular disease, neurodegenerative diseases, etc.

How to detect mutations in the Human FGFR2 gene?

A: The detection of FGFR2 gene mutations can be achieved through various methods, including but not limited to: polymerase chain reaction (PCR), sequencing analysis, fluorescence in situ hybridization (FISH), etc. These methods can detect point mutations, insertions/deletions, rearrangements, and other types of gene mutations, thereby helping researchers understand the relationship between the gene and the disease and the effectiveness of drug treatment.

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