Human AREG mRNA

Name: Human AREG mRNA
SKU: PMRN-0091
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : PMRN-0091

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Product Information

Cat. No.	PMRN-0091
Description	The AREG mRNA encodes the human amphiregulin (AREG) protein, a member of the epidermal growth factor family. AREG interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells, and inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland, oocyte and bone tissue development.
Gene Type	Other
RNA Type	mRNA
Gene Name	AREG
Species	Homo sapiens (Human)
Alias	AR, AREGB, CRDGF, SDGF
Features	• mRNA synthesized on error free sequence verified plasmid DNA template • 100% replacement of UTP with modified nucleotides 5-Methoxy-UTP • Cap 1 Capping and poly-A tailed incorporated • Degrades the DNA template after RNA synthesis with DNase
Sequence	MRAPLLPPAP VVLSLLILGS GHYAAGLDLN DTYSGKREPF SGDHSADGFE VTSRSEMSSG SEISPVSEMP SSSEPSSGAD YDYSEEYDNE PQIPGYIVDD SVRVEQVVKP PQNKTESENT SDKPKRKKKG GKNGKNRRNR KKKNPCNAEF QNFCIHGECK YIEHLEAVTC KCQQEYFGER CGEKSMKTHS MIDSSLSKIA LAAIAAFMSA VILTAVAVIT VQLRRQYVRK YEGEAEERKK LRQENGNVHA IA
Storage	Store at or below -70°C. Avoid repeated freeze/thaw cycles. Aliquot if necessary using RNase-free equipment, reagents, pipet tips, tubes, and containers.

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What is Human AREG mRNA?

A: Human AREG mRNA is a messenger RNA that encodes the endogenous human growth factor Amphiregulin (AREG).

What cells produce Human AREG mRNA?

A: Human AREG mRNA is mainly produced in tumor cells and certain immune cells in the human body.

What is AREG?

A: Amphiregulin (AREG) is a growth factor of the EGF family that activates the signaling pathway for cell growth and division by binding to EGFR (epidermal growth factor receptor).

What is the role of Human AREG mRNA?

A: Human AREG mRNA has certain physiological functions in the human body. The AREG growth factor encoded by it can stimulate the growth of tumor cells and regulate the function of immune cells.

What is the relationship between Human AREG mRNA and cancer?

A: Some studies suggest that the expression level of Human AREG mRNA may increase in certain types of cancer, making it a potential biomarker for cancer diagnosis and treatment.

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