Human IL20 mRNA

Name: Human IL20 mRNA
SKU: PMRN-0158

For research use only. Not intended for any clinical use.

Cat.No.

PMRN-0158

Description

The IL20 mRNA encodes the human interleukin 20 (IL20) protein, a proinflammatory and angiogenic cytokine that may involves in epidermal function and psoriasis.

Alias

IL-20; IL10D; ZCYTO10

Features

• mRNA synthesized on error free sequence verified plasmid DNA template
• 100% replacement of UTP with modified nucleotides 5-Methoxy-UTP
• Cap 1 Capping and poly-A tailed incorporated
• Degrades the DNA template after RNA synthesis with DNase

Sequence

MKASSLAFSL LSAAFYLLWT PSTGLKTLNL GSCVIATNLQ EIRNGFSEIR GSVQAKDGNI DIRILRRTES LQDTKPANRC CLLRHLLRLY LDRVFKNYQT PDHYTLRKIS SLANSFLTIK KDLRLCHAHM TCHCGEEAMK KYSQILSHFE KLEPQAAVVK ALGELDILLQ WMEETE

Species

Homo sapiens (Human)

Storage

Store at or below -70°C. Avoid repeated freeze/thaw cycles. Aliquot if necessary using RNase-free equipment, reagents, pipet tips, tubes, and containers.

Publications

Q & A

Customer Reviews

Customer Q&As

What is Human IL20 mRNA?

A: Human IL20 mRNA is the messenger RNA of the human IL-20 gene. IL-20 is a cytokine that participates in immune and inflammatory responses.

What is the role of Human IL20 mRNA in the human body?

A: The function of Human IL20 mRNA is to encode the IL-20 protein. IL-20 is a cytokine involved in inflammatory and immune responses, which can act on cell surface receptors in multiple organs such as the skin, lungs, and kidneys, exerting its biological effects.

In which cells is Human IL20 mRNA expressed?

A: Human IL20 mRNA is mainly expressed in monocytes/macrophages, lymphocytes, and epithelial cells.

What diseases are associated with Human IL20 mRNA?

A: Research has shown that Human IL20 mRNA is associated with some inflammatory and autoimmune diseases, such as psoriasis, rheumatoid arthritis, and systemic lupus erythematosus. In these diseases, the expression level of IL-20 may change, thereby affecting the progression and prognosis of the disease.

How to regulate the expression of Human IL20 mRNA?

A: The expression of IL-20 gene can be regulated by altering its transcription and post-transcriptional modification processes. Some drugs can also inhibit or induce the expression of IL-20. In addition, regulating intracellular signaling pathways can also affect the expression of IL-20.

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