Transfected Stable Cell Lines
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Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Premade Virus Particles
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Premade AAV, adenovirus, lentivirus particles, safe, stable, in stock.
Virus-Like Particles (VLPs)
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Advanced VLPs for vaccine development (Chikungunya, Dengue, SARS-CoV-2), gene therapy (AAV1 & AAV9), and drug screening (SSTR2, CCR5).
Oligonucleotide Products
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Accelerate your research with cost-effective LncRNA qPCR Array Technology.
RNA Interference Products
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Human Druggable Genome siRNA Library enables efficient drug target screening.
Recombinant Drug Target Proteins
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Providing functional, high-purity recombinant proteins—including membrane proteins and nanodiscs—to overcome bottlenecks in drug screening and target validation.
Clones
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Ready-to-use clones for streamlined research and development.
Kits
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Chromogenic LAL Endotoxin Assay Kit ensures precise, FDA-compliant endotoxin quantification for biosafety testing.
Enzymes
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Powerful Tn5 Transposase for DNA insertion and random library construction.
Aptamers
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Aptamers for key proteins like ACVR1A, Akt, EGFR, and VEGFR.
Adjuvants
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Enhance immune responses with high-purity, potent CpG ODNs.
Laboratory Equipment
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Effortlessly streamline DNA extraction with CB™ Magnetic-Nanoparticle Systems.
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Fast proposals, regular updates, and detailed reports; strict quality control, and contamination-free cells; knockout results in 4-6 weeks.
Target-based Drug Discovery Service
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Target identification, validation, and screening for drug discovery and therapeutic development.
Custom Viral Service
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Unbeatable pricing, fully customizable viral packaging services (covering 30,000+ human genes, 200+ mammals, 50+ protein tags).
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End-to-end antibody development support, from target to validation, enabling clients to rapidly obtain application-ready antibodies.
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Comprehensive solutions covering design, development, and validation to ensure conjugated drugs with consistent quality and clinical potential.
Protein Degrader Service
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Harness the power of protein degraders for precise protein degradation, expanding druggable targets and enhancing therapeutic effectiveness for cutting-edge drug discovery.
Nucleotides Service
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Custom synthesis of oligonucleotides, primers, and probes for gene editing, PCR, and RNA studies.
Custom RNA Service
Custom RNA ServicePrecise | Flexible | GMP-ReadyCustom
RNA design, synthesis, and manufacturing—covering mRNA, saRNA, circRNA, and RNAi. Fast turnaround, rigorous QC, and seamless transition from research to GMP production.
Custom Libraries Construction Service
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Custom cDNA, genomic, and mutagenesis libraries for drug discovery, screening, and functional genomics.
Gene Editing Services
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Gene editing solutions for gene editing, knockouts, knock-ins, and customized genetic modifications. Integrated multi-platform solutions for one-stop CRISPR sgRNA library synthesis and gene screening services
Microbe Genome Editing Service
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Enhance microbial productivity with advanced genome editing using Rec-mediated recombination and CRISPR/Cas9 technologies.
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Genetic modification for crop improvement, biotechnology, and plant-based research solutions.
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Plant-based protein expression systems for biopharmaceuticals, enzyme production, and research.
Aptamers Service
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Revolutionizing drug delivery and diagnostic development with next-generation high-throughput aptamer selection and synthesis technologies.
CGT Biosafety Testing
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Internationally certified evaluation system for biologics, gene therapies, nucleic acid drugs, and vaccines.
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Stable expression over 15 generations with rapid cell line development in just 3 months.
Supports adherent and suspension cell lines, offering MCB, WCB, and PCB establishment.
GMP mRNA Production
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Scalable mRNA production from milligrams to grams, with personalized process design for sequence optimization, cap selection, and nucleotide modifications, all in one service.
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Our plasmid production services span Non-GMP, GMP-Like, and GMP-Grade levels, with specialized options for linearized plasmids.
GMP Viral Vector Manufacturing
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Advanced platforms for AAV, adenovirus, lentivirus, and retrovirus production, with strict adherence to GMP guidelines and robust quality control.
AI-Driven Gene Editing and Therapy
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AI-powered one-click design for customized CRISPR gene editing strategy development.
AI-Antibody Engineering Fusion
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AI and ML algorithms accelerate antibody screening and predict new structures, unlocking unprecedented possibilities in antibody engineering.
AI-Driven Enzyme Engineering
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High-throughput enzyme activity testing with proprietary datasets and deep learning models for standardized and precise enzyme engineering design.
AI-Enhanced Small Molecule Screening
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Leverage AI to uncover hidden high-potential small molecules, prioritize leads intelligently, and reduce costly trial-and-error in early drug discovery.
AI-Driven Protein Degrader Drug Development
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Use AI-guided design to optimize protein degraders, addressing design complexity and enhancing efficacy while shortening development timelines.
A: Human IL1B mRNA refers to human interleukin-1 β (Interleukin-1beta) messenger RNA molecule. IL1B is a cytokine secreted by cells, involved in regulating inflammation and immune responses.
A: Human IL1B mRNA encoded protein - interleukin-1 β， It is an important inflammatory mediator. It is involved in regulating the activation of immune cells, the occurrence and development of inflammatory reactions, and the development of some diseases.
A: Human IL1B mRNA is mainly expressed in immune cells, such as macrophages, Monocyte, lymphocytes, etc. In addition, some non immune cells such as epithelial cells and endothelial cells can also express IL-1B mRNA.
A: The expression of Human IL1B mRNA is influenced by various regulatory factors, including inflammatory mediators, cytokines, pathogen infections, and cellular stress. These regulatory factors can regulate the transcription and stability of IL1B mRNA by activating transcription factors and signaling pathways.
A: Human IL1B mRNA plays an important role in many inflammatory diseases, such as rheumatoid arthritis, Inflammatory bowel disease, autoimmune diseases, etc. It is also related to the occurrence and development of certain tumors.
A: Yes, some studies show that Human IL1B mRNA plays an important role in the occurrence and development of cardiovascular diseases. It is involved in the inflammatory reaction of Atherosclerosis, vascular endothelial dysfunction and other processes.
A: The commonly used methods for detecting Human IL1B mRNA include real-time quantitative PCR, Northern blotting, in situ hybridization, etc. These methods can quantitatively or qualitatively measure the expression level of IL1B mRNA.
A: Yes, some drugs can inhibit the expression of Human IL1B mRNA, such as IL-1 receptor antagonists (IL-1RA) and IL-1 β Antibodies, etc. These drugs can be used to treat diseases related to IL1B overexpression.
A: Due to its important role in various inflammatory diseases, Human IL1B mRNA is considered a potential therapeutic target. Some drugs have been developed to inhibit the expression of IL-1B or the activity of its receptors for the treatment of related diseases.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
I can use the drug immediately after I get it by adding the corresponding dissolution reagent, and no special processing is required before it can be used.
United Kingdom
10/09/2021
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| Cat.No. | Product Name | Price |
|---|---|---|
| PMRNL-0001 | EGFP mRNA (no modification) | Inquiry |
| PMRN-0273 | Human TLR7 mRNA | Inquiry |
| PMRN-0176 | Human TNFSF8 mRNA | Inquiry |
| PMRN-0025 | Human TBX5 mRNA | Inquiry |
| PMRN-0242 | Human ACVR1 mRNA | Inquiry |
| PMRN-0228 | Human IL20RA mRNA | Inquiry |
| PMRN-0011 | Human LIN28A mRNA | Inquiry |
| PMRN-0066 | Human FGF6 mRNA | Inquiry |
| PMRN-0169 | Human IL34 mRNA | Inquiry |
| PMRN-0283 | Human PAX7 mRNA | Inquiry |
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