Human IFNLR1 mRNA

Name: Human IFNLR1 mRNA
SKU: PMRN-0211
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : PMRN-0211

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Product Information

Cat. No.	PMRN-0211
Description	The IFNLR1 mRNA encodes the human interferon lambda receptor 1 (IFNLR1) protein, a member of the class II cytokine receptor family. IFNLR1, interleukine 10 receptor and beta (IL10RB) form a receptor complex which has been shown to interact with three closely related cytokines, including interleukin 28A (IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29).
Gene Type	Other
RNA Type	mRNA
Gene Name	IFNLR1
Species	Homo sapiens (Human)
Alias	IFNLR; LICR2; IL28RA; CRF2/12; IL-28R1
Features	• mRNA synthesized on error free sequence verified plasmid DNA template • 100% replacement of UTP with modified nucleotides 5-Methoxy-UTP • Cap 1 Capping and poly-A tailed incorporated • Degrades the DNA template after RNA synthesis with DNase
Sequence	MAGPERWGPL LLCLLQAAPG RPRLAPPQNV TLLSQNFSVY LTWLPGLGNP QDVTYFVAYQ SSPTRRRWRE VEECAGTKEL LCSMMCLKKQ DLYNKFKGRV RTVSPSSKSP WVESEYLDYL FEVEPAPPVL VLTQTEEILS ANATYQLPPC MPPLDLKYEV AFWKEGAGNK TLFPVTPHGQ PVQITLQPAA SEHHCLSART IYTFSVPKYS KFSKPTCFLL EVPEANWAFL VLPSLLILLL VIAAGGVIWK TLMGNPWFQR AKMPRALDFS GHTHPVATFQ PSRPESVNDL FLCPQKELTR GVRPTPRVRA PATQQTRWKK DLAEDEEEED EEDTEDGVSF QPYIEPPSFL GQEHQAPGHS EAGGVDSGRP RAPLVPSEGS SAWDSSDRSW ASTVDSSWDR AGSSGYLAEK GPGQGPGGDG HQESLPPPEF SKDSGFLEEL PEDNLSSWAT WGTLPPEPNL VPGGPPVSLQ TLTFCWESSP EEEEEARESE IEDSDAGSWG AESTQRTEDR GRTLGHYMAR
Storage	Store at or below -70°C. Avoid repeated freeze/thaw cycles. Aliquot if necessary using RNase-free equipment, reagents, pipet tips, tubes, and containers.

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What is Human IFNLR1 mRNA?

A: Human IFNLR1 mRNA is a molecule that encodes human interferon- λ Receptor 1 (Interferon)- λ Receiver 1, abbreviated as IFNLR1. IFNLR1 is a receptor that plays a crucial role in the antiviral immune response.

What is the main function of Human IFNLR1 mRNA?

A: The main function of Human IFNLR1 mRNA is to produce and secrete IFNLR1. IFNLR1 is a cell surface receptor that can bind to interferon- λ Interferon- λ, Abbreviated as IFN- λ), Activate downstream signaling pathways to induce the expression of antiviral genes and exert antiviral effects.

In which cells is Human IFNLR1 mRNA expressed?

A: Human IFNLR1 mRNA can be expressed in various cells, including liver cells, alveolar epithelial cells, digestive tract epithelial cells, etc. These cells express IFNLR1 when infected with the virus to initiate an antiviral immune response.

What diseases are associated with Human IFNLR1 mRNA?

A: Studies have shown that Human IFNLR1 mRNA is associated with a variety of viral infectious diseases. For example, in hepatitis C virus (HCV) infection, the expression level of IFNLR1 can affect the replication and clearance of the virus. In addition, IFNLR1 also plays an important antiviral role in respiratory syncytial virus (RSV) and parainfluenza virus infections.

How is the expression of Human IFNLR1 mRNA regulated?

A: The expression of Human IFNLR1 mRNA is regulated by various factors, including transcription factors, signal transduction pathways, environmental factors, etc. For example, NF- κ The B and STAT signaling pathways can promote the expression of IFNLR1. In addition, viral infection can also induce the expression of IFNLR1.

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