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Human HGF mRNA

For research use only. Not intended for any clinical use.
Cat.No.
PMRN-0052
Description
The HGF mRNA encodes the human hepatocyte growth factor (HGF) protein, a protein that binds to the hepatocyte growth factor receptor to regulate cell growth, cell motility and morphogenesis in numerous cell and tissue types. It also plays a role in angiogenesis, tumorogenesis, and tissue regeneration.
Alias
SF; HGFB; HPTA; F-TCF; DFNB39
Features
• mRNA synthesized on error free sequence verified plasmid DNA template
• 100% replacement of UTP with modified nucleotides 5-Methoxy-UTP
• Cap 1 Capping and poly-A tailed incorporated
• Degrades the DNA template after RNA synthesis with DNase
Sequence
MWVTKLLPAL LLQHVLLHLL LLPIAIPYAE GQRKRRNTIH EFKKSAKTTL IKIDPALKIK TKKVNTADQC ANRCTRNKGL PFTCKAFVFD KARKQCLWFP FNSMSSGVKK EFGHEFDLYE NKDYIRNCII GKGRSYKGTV SITKSGIKCQ PWSSMIPHEH SFLPSSYRGK DLQENYCRNP RGEEGGPWCF TSNPEVRYEV CDIPQCSEVE CMTCNGESYR GLMDHTESGK ICQRWDHQTP HRHKFLPERY PDKGFDDNYC RNPDGQPRPW CYTLDPHTRW EYCAIKTCAD NTMNDTDVPL ETTECIQGQG EGYRGTVNTI WNGIPCQRWD SQYPHEHDMT PENFKCKDLR ENYCRNPDGS ESPWCFTTDP NIRVGYCSQI PNCDMSHGQD CYRGNGKNYM GNLSQTRSGL TCSMWDKNME DLHRHIFWEP DASKLNENYC RNPDDDAHGP WCYTGNPLIP WDYCPISRCE GDTTPTIVNL DHPVISCAKT KQLRVVNGIP TRTNIGWMVS LRYRNKHICG GSLIKESWVL TARQCFPSRD LKDYEAWLGI HDVHGRGDEK CKQVLNVSQL VYGPEGSDLV LMKLARPAVL DDFVSTIDLP NYGCTIPEKT SCSVYGWGYT GLINYDGLLR VAHLYIMGNE KCSQHHRGKV TLNESEICAG AEKIGSGPCE GDYGGPLVCE QHKMRMVLGV IVPGRGCAIP NRPGIFVRVA YYAKWIHKII LTYKVPQS
Species
Homo sapiens (Human)
Storage
Store at or below -70°C. Avoid repeated freeze/thaw cycles. Aliquot if necessary using RNase-free equipment, reagents, pipet tips, tubes, and containers.

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Q & A

Customer Reviews

Customer Q&As
What role does The HGF mRNA play in human hepatocytes?

A: HGF mRNA encodes the human hepatocyte growth factor (HGF) protein, which binds to the hepatocyte growth factor receptor and regulates cell growth, cell motility and morphogenesis in numerous cell and tissue types.

What biological activities are human HGF mRNAs involved in

A: HGF mRNA also plays a role in angiogenesis, tumorigenesis and tissue regeneration.

How does HGF mRNA-LNP induce hepatocyte proliferation?

A: In the liver, almost all hepatocytes are transfected with endothelial cells and Kupffer cell subpopulations─. In the in vivo homeostasis, HGF mRNA-LNP efficiently induced hepatocyte proliferation.

What is the molecular weight of recombinant human HGF?

A: Secreted recombinant human HGF consists of a signal peptide cleaved to 697 amino acids with a predicted molecular weight of 79.7 kDa. HGF single chains can be processed into active forms of disulfide-bonded heterodimers of the a- and β-chains.

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Customer Reviews
Fast & Convenient

Directly remove the substance from the powder cartridge for targeted injection modulation. Putting it in the ice box can be taken away directly, but it is better to split it.

United States

02/28/2023

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