Human FGFRL1 mRNA

Name: Human FGFRL1 mRNA
SKU: PMRN-0111

For research use only. Not intended for any clinical use.

Cat.No.

PMRN-0111

Description

The FGFRL1 mRNA encodes the human fibroblast growth factor receptor like 1 (FGFRL1) protein, a member of the fibroblast growth factor receptor (FGFR) family. The extracellular portion of FGFRL1 protein can interact with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation.

Alias

FGFR-5, FGFR5, FHFR

Features

• mRNA synthesized on error free sequence verified plasmid DNA template
• 100% replacement of UTP with modified nucleotides 5-Methoxy-UTP
• Cap 1 Capping and poly-A tailed incorporated
• Degrades the DNA template after RNA synthesis with DNase

Sequence

MTPSPLLLLL LPPLLLGAFP PAAAARGPPK MADKVVPRQV ARLGRTVRLQ CPVEGDPPPL TMWTKDGRTI HSGWSRFRVL PQGLKVKQVE REDAGVYVCK ATNGFGSLSV NYTLVVLDDI SPGKESLGPD SSSGGQEDPA SQQWARPRFT QPSKMRRRVI ARPVGSSVRL KCVASGHPRP DITWMKDDQA LTRPEAAEPR KKKWTLSLKN LRPEDSGKYT CRVSNRAGAI NATYKVDVIQ RTRSKPVLTG THPVNTTVDF GGTTSFQCKV RSDVKPVIQW LKRVEYGAEG RHNSTIDVGG QKFVVLPTGD VWSRPDGSYL NKLLITRARQ DDAGMYICLG ANTMGYSFRS AFLTVLPDPK PPGPPVASSS SATSLPWPVV IGIPAGAVFI LGTLLLWLCQ AQKKPCTPAP APPLPGHRPP GTARDRSGDK DLPSLAALSA GPGVGLCEEH GSPAAPQHLL GPGPVAGPKL YPKLYTDIHT HTHTHSHTHS HVEGKVHQHI HYQC

Species

Homo sapiens (Human)

Storage

Store at or below -70°C. Avoid repeated freeze/thaw cycles. Aliquot if necessary using RNase-free equipment, reagents, pipet tips, tubes, and containers.

Publications

Q & A

Customer Reviews

Customer Q&As

What is Human FGFRL1 mRNA?

A: Human FGFRL1 mRNA is a messenger RNA of the human FGFRL1 gene. FGFRL1, also known as FGF receptor like 1, is a protein kinase receptor with mitogenic activity that participates in angiogenesis and bone development.

What is the role of Human FGFRL1 mRNA in the human body?

A: The function of Human FGFRL1 mRNA is to encode the FGFRL1 protein, which is a cell surface receptor that can bind to members of the FGF (fibroblast growth factor) family, such as FGF-1, FGF-2, etc., thereby triggering intracellular signaling pathways and promoting cell growth and division.

In which cells is Human FGFRL1 mRNA expressed?

A: Human FGFRL1 mRNA is expressed in various cells, including bone cells, myocardial cells, and endothelial cells.

What diseases are associated with Human FGFRL1 mRNA?

A: Research has shown that Human FGFRL1 mRNA is associated with some diseases, including osteoporosis, heart disease, cancer, etc. In these diseases, the expression level of FGFRL1 may change, thereby affecting the progression and prognosis of the disease.

What is the relationship between Human FGFRL1 mRNA and treatment?

A: Understanding the expression level and regulatory mechanism of Human FGFRL1 mRNA can provide new ideas and methods for the treatment of some diseases. For example, inhibiting the expression of FGFRL1 can prevent tumor growth and spread. Meanwhile, inducing the expression of FGFRL1 may contribute to the treatment of diseases such as osteoporosis and heart disease.

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