Human CCR1 mRNA

Name: Human CCR1 mRNA
SKU: PMRN-0193

For research use only. Not intended for any clinical use.

Cat.No.

PMRN-0193

Description

The CCR1 mRNA encodes the human C-C motif chemokine receptor 1 (CCR1) protein, a member of the beta chemokine receptor family. Chemokines and their receptors are critical for the recruitment of effector immune cells to the site of inflammation.

Alias

CD191, CKR-1, CKR1, CMKBR1, HM145, MIP1aR, SCYAR1

Features

• mRNA synthesized on error free sequence verified plasmid DNA template
• 100% replacement of UTP with modified nucleotides 5-Methoxy-UTP
• Cap 1 Capping and poly-A tailed incorporated
• Degrades the DNA template after RNA synthesis with DNase

Sequence

METPNTTEDY DTTTEFDYGD ATPCQKVNER AFGAQLLPPL YSLVFVIGLV GNILVVLVLV QYKRLKNMTS IYLLNLAISD LLFLFTLPFW IDYKLKDDWV FGDAMCKILS GFYYTGLYSE IFFIILLTID RYLAIVHAVF ALRARTVTFG VITSIIIWAL AILASMPGLY FSKTQWEFTH HTCSLHFPHE SLREWKLFQA LKLNLFGLVL PLLVMIICYT GIIKILLRRP NEKKSKAVRL IFVIMIIFFL FWTPYNLTIL ISVFQDFLFT HECEQSRHLD LAVQVTEVIA YTHCCVNPVI YAFVGERFRK YLRQLFHRRV AVHLVKWLPF LSVDRLERVS STSPSTGEHE LSAGF

Species

Homo sapiens (Human)

Storage

Store at or below -70°C. Avoid repeated freeze/thaw cycles. Aliquot if necessary using RNase-free equipment, reagents, pipet tips, tubes, and containers.

Publications

Q & A

Customer Reviews

Customer Q&As

What is Human CCR1 mRNA?

A: Human CCR1 mRNA is the messenger RNA of the human CCR1 gene. CCR1 (C-C chemokine receptor type 1) is a G protein coupled receptor that participates in processes such as cell migration, inflammatory response, and immune regulation.

What is the role of Human CCR1 mRNA in the human body?

A: The function of Human CCR1 mRNA is to encode the CCR1 protein. CCR1 can participate in various biological processes in the human body, including immune cell migration, inflammatory response, and tumor development. It can recognize and respond to C-C chemokines, regulate cell migration and activation, and play an important role in maintaining in vivo balance and tissue repair.

In which cells is Human CCR1 mRNA expressed?

A: Human CCR1 mRNA is expressed in various cells, including immune cells, endothelial cells, smooth muscle cells, and tumor cells. Its expression level can be induced or inhibited by various factors such as inflammatory factors, cytokines, and chemicals.

What diseases are associated with Human CCR1 mRNA?

A: Research has shown that Human CCR1 mRNA is associated with some inflammatory diseases, autoimmune diseases, and tumors. In these diseases, the expression level of CCR1 may change, thereby affecting the progression and prognosis of the disease

What is the structure of Human CCR1?

A: The structure of Human CCR1 is similar to other G protein coupled receptors, consisting of extracellular domain, transmembrane domain, and intracellular domain. The extracellular domain contains ligand binding sites, the transmembrane domain consists of seven transmembrane helices, and the intracellular domain contains binding sites for G protein coupled receptor kinase (GRK) and arrestin.

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