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Human AMHR2 mRNA

For research use only. Not intended for any clinical use.
Cat.No.
PMRN-0248
Description
The AMHR2 mRNA encodes the human anti-Mullerian hormone receptor type 2 (AMHR2) protein, a receptor for the anti-Mullerian hormone (AMH).
Alias
AMHR, MISR2, MISRII, MRII
Features
• mRNA synthesized on error free sequence verified plasmid DNA template
• 100% replacement of UTP with modified nucleotides 5-Methoxy-UTP
• Cap 1 Capping and poly-A tailed incorporated
• Degrades the DNA template after RNA synthesis with DNase
Sequence
MLGSLGLWAL LPTAVEAPPN RRTCVFFEAP GVRGSTKTLG ELLDTGTELP RAIRCLYSRC CFGIWNLTQD RAQVEMQGCR DSDEPGCESL HCDPSPRAHP SPGSTLFTCS CGTDFCNANY SHLPPPGSPG TPGSQGPQAA PGESIWMALV LLGLFLLLLL LLGSIILALL QRKNYRVRGE PVPEPRPDSG RDWSVELQEL PELCFSQVIR EGGHAVVWAG QLQGKLVAIK AFPPRSVAQF QAERALYELP GLQHDHIVRF ITASRGGPGR LLSGPLLVLE LHPKGSLCHY LTQYTSDWGS SLRMALSLAQ GLAFLHEERW QNGQYKPGIA HRDLSSQNVL IREDGSCAIG DLGLALVLPG LTQPPAWTPT QPQGPAAIME AGTQRYMAPE LLDKTLDLQD WGMALRRADI YSLALLLWEI LSRCPDLRPD SSPPPFQLAY EAELGNTPTS DELWALAVQE RRRPYIPSTW RCFATDPDGL RELLEDCWDA DPEARLTAEC VQQRLAALAH PQESHPFPES CPRGCPPLCP EDCTSIPAPT ILPCRPQRSA CHFSVQQGPC SRNPQPACTL SPV
Species
Homo sapiens (Human)
Storage
Store at or below -70°C. Avoid repeated freeze/thaw cycles. Aliquot if necessary using RNase-free equipment, reagents, pipet tips, tubes, and containers.

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Q & A

Customer Reviews

Customer Q&As
What is Human AMHR2mRNA?

A: Human AMHR2 mRNA refers to the messenger RNA of human anti M ü llerian Hormone receptor type 2. It is a gene product that encodes the AMHR2 protein.

What role does AMHR2 protein play in the human body?

A: AMHR2 protein is an important component of anti M ü llerian Hormone receptor type 2, which plays a key role in embryonic development and reproductive system. It is involved in regulating male and female gender development, as well as ovarian and testicular function.

Which chromosome is the AMHR2 gene located on?

A: AMHR2 gene is located on Chromosome 12 of the Human genome.

What diseases can AMHR2 gene mutations cause?

A: AMHR2 gene mutation may lead to M ü llerian insufficiency syndrome (MRKH syndrome), which is a disease related to abnormal development of Female reproductive system. The characteristics of this disease include developmental defects in the uterus and vagina.

What is the expression pattern of AMHR2mRNA?

A: AMHR2 mRNA is mainly expressed in early embryonic development and the reproductive system, and it plays a role in both male and female gender development.

In which tissues is AMHR2mRNA expressed?

A: AMHR2 mRNA is mainly expressed in reproductive system tissues, such as ovaries, vagina, testes, etc. In addition, there are also low levels of expression in some other tissues.

What is the function of AMHR2 mRNA?

A: The function of AMHR2 mRNA is to code AMHR2 protein, which is an important component of anti M ü llerian Hormone receptor type 2. It participates in regulating the development and function of the reproductive system by binding to anti M ü llerian hormones.

What diseases are associated with AMHR2mRNA?

A: In addition to MRKH syndrome, AMHR2 gene mutations are also associated with other Reproductive system disease, such as ovarian cancer and Testicular cancer. Studying AMHR2 mRNA can help to gain a deeper understanding of the mechanisms underlying these diseases.

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Customer Reviews
Worked Very Well

AMHR2 mRNA reagent is an easy to use, high expression reagent. I have successfully expressed the protein after using it for g rickets-related pathology experiments.

United States

04/11/2023

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