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human SMAD6 ORF clone (NM_005585.4)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCH083338

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Product Information

Gene Information

Cat. No. CDCH083338
Description Homo sapiens SMAD family member 6 (SMAD6), transcript variant 1, mRNA.
Product Type ORF clone
Gene Abbr SMAD6
Gene Name SMAD6 SMAD family member 6 [ Homo sapiens ]
Species Human
ORF Size 1491bp
Format purified plasmid or bacterial stock
Vector pDONR
Warning Please note that the protein for this clone has been annotated or predicted in the UNIPROT database to have a signal peptide. Placing a tag at the N-terminus of this protein may result in loss of the signal peptide function.
Gene Name SMAD6 SMAD family member 6 [ Homo sapiens ]
Gene Symbol SMAD6
Synonyms AOVD2; MADH6; MADH7; HsT17432
Gene ID 4091
Uni Prot ID O43541
m RNA Refseq NM_001142861.2
Protein Refseq NP_001136333.1
Chromosome Location 15q21-q22
Function I-SMAD binding; R-SMAD binding; chromatin binding; co-SMAD binding; protein binding; sequence-specific DNA binding transcription factor activity; transcription regulatory region DNA binding; transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity; transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity; type I activin receptor binding; type I transforming growth factor beta receptor binding; ubiquitin protein ligase binding;
Pathway BMP receptor signaling, organism-specific biosystem; BMP signalling and regulation, organism-specific biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; Integrated Breast Cancer Pathway, organism-specific biosystem; Integrated Pancreatic Cancer Pathway, organism-specific biosystem; Signal Transduction, organism-specific biosystem;
MIM 602931
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