shRNA set against Human SMAD6 (NM_005585.4)

Name: shRNA set against Human SMAD6 (NM_005585.4)
SKU: SHH413008
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : SHH413008

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Product Information

Gene Information

Cat. No.	SHH413008
Description	The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr	SMAD6
Gene Name	SMAD6 SMAD family member 6 [ Homo sapiens ]
Species	Human
Report Gene	GFP
Storage	The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.

Gene Name	SMAD6 SMAD family member 6 [ Homo sapiens ]
Gene Symbol	SMAD6
Synonyms	AOVD2; MADH6; MADH7; HsT17432
Gene ID	4091
Uni Prot ID	O43541
m RNA Refseq	NM_001142861.2
Protein Refseq	NP_001136333.1
Chromosome Location	15q21-q22
Function	I-SMAD binding; R-SMAD binding; chromatin binding; co-SMAD binding; protein binding; sequence-specific DNA binding transcription factor activity; transcription regulatory region DNA binding; transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity; transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity; type I activin receptor binding; type I transforming growth factor beta receptor binding; ubiquitin protein ligase binding;
Pathway	BMP receptor signaling, organism-specific biosystem; BMP signalling and regulation, organism-specific biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; Integrated Breast Cancer Pathway, organism-specific biosystem; Integrated Pancreatic Cancer Pathway, organism-specific biosystem; Signal Transduction, organism-specific biosystem;
MIM	602931

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