Panoply™ Human SMAD6 Over-expressing Stable Cell Line

Name: Panoply™ Human SMAD6 Over-expressing Stable Cell Line
SKU: CSC-SC014716
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-SC014716

Host Cell : HEK293 (CHO and other cell types are also available) Size : >1x10⁶ frozen cells/vial

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Cell Line Information

Cell Culture Information

Safety and Packaging

Gene Information

Cat. No.	CSC-SC014716
Description	Using Creative Biogene's proprietary lentiviral vectors, we subclone the target gene into lentivector, generate the lentivirus particles, sequentially infect the cell line HEK293 (other cell types are also available according to your requirements), and select the clones constantly expressing target gene at high level.
Target Gene	SMAD6
Gene Species	Homo sapiens (Human)
Host Cell	HEK293 (CHO and other cell types are also available)
Host Cell Species	Species varies
Applications	1. Gene expression studies 2. Signaling pathway research 3. Drug screening and toxicology 4. Disease research
Size	2 × 10^6 cells / vial
Stability	Validated for at least 10 passages
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid nitrogen
Shipping	Dry Ice

Revival

Rapidly thaw cells in a 37°C water bath. Transfer contents into a tube containing pre-warmed media. Centrifuge cells and seed into a 25 cm2 flask containing pre-warmed media.

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	SMAD6 SMAD family member 6 [ Homo sapiens ]
Gene Symbol	SMAD6
Synonyms	AOVD2; MADH6; MADH7; HsT17432
Gene ID	4091
Uni Prot ID	O43541
m RNA Refseq	NM_001142861.2
Protein Refseq	NP_001136333.1
Chromosome Location	15q21-q22
Function	I-SMAD binding; R-SMAD binding; chromatin binding; co-SMAD binding; protein binding; sequence-specific DNA binding transcription factor activity; transcription regulatory region DNA binding; transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity; transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity; type I activin receptor binding; type I transforming growth factor beta receptor binding; ubiquitin protein ligase binding;
Pathway	BMP receptor signaling, organism-specific biosystem; BMP signalling and regulation, organism-specific biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; Integrated Breast Cancer Pathway, organism-specific biosystem; Integrated Pancreatic Cancer Pathway, organism-specific biosystem; Signal Transduction, organism-specific biosystem;
MIM	602931

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