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Panoply™ Human SMAD6 Knockdown Stable Cell Line

Cat.No.
CSC-DC014716
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
SMAD6
Synonyms
AOVD2; MADH6; MADH7; HsT17432
Gene ID
UniProt ID
O43541
mRNA Refseq
Protein Refseq
Chromosome Location
15q21-q22
Function
I-SMAD binding; R-SMAD binding; chromatin binding; co-SMAD binding; protein binding; sequence-specific DNA binding transcription factor activity; transcription regulatory region DNA binding; transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity; transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity; type I activin receptor binding; type I transforming growth factor beta receptor binding; ubiquitin protein ligase binding;
Pathway
BMP receptor signaling, organism-specific biosystem; BMP signalling and regulation, organism-specific biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; Integrated Breast Cancer Pathway, organism-specific biosystem; Integrated Pancreatic Cancer Pathway, organism-specific biosystem; Signal Transduction, organism-specific biosystem;
MIM

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