human PAH (NM_000277) lentivirus particles

Name: human PAH (NM_000277) lentivirus particles
SKU: LV20892L
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : LV20892L

Storage : -80℃ Shipping : Frozen on dry ice

Titer: Size:

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Virus Particles Information

Quality Control

Gene Information

Cat. No.	LV20892L
Description	Lentiviral particles of phenylalanine hydroxylase (PAH).
Product Type	Premade Lentivirus Particles
Gene	PAH
Species	Human
Insert Size	1359 bp
Titer	Varies lot by lot, for example, ≥110^7 TU/mL, ≥110^8 TU/mL, ≥1*10^9 TU/mL etc.
Size	Varies lot by lot, for example, 100 ul, 500 ul, 1 mL etc.
Storage	Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping	Frozen on dry ice

Summary	Creative Biogene ensures high-quality lentivirus particles by optimizing and standardizing production protocols and performing stringent quality control (QC). The specific QC experiments performed vary between lentivirus particle lots.
Mycoplasma	Creative Biogene routinely tests for mycoplasma contamination using a mycoplasma detection kit. Cell lines are maintained for approximately 20 passages before being discarded and replaced with a new vial of early passage cells. Approximately 2 weeks after thawing, cell culture supernatants are tested for mycoplasma contamination. Creative Biogene ensures that lentiviral products are free of mycoplasma contamination.
Purity	Creative Biogene evaluates the level of impurities, such as residual host cell DNA or proteins, in prepared lentiviral vectors to ensure they meet quality standards.
Sterility	The lentiviral samples were inoculated into cell culture medium for about 5 days and the growth of bacteria and fungi was tested. Creative Biogene ensures that the lentiviral products are free of microbial contamination.
Transducibility	Upon requirement, Creative Biogene can perform in vitro or in vivo transduction assays to evaluate the ability of lentivirus to deliver genetic material into target cells, and assess gene expression and functional activities.
Proviral Identity Confirmation	All Creative Biogene lentiviral vectors are confirmed to have correctly integrated provirus using PCR. This test involves transducing cells with serial dilutions of the lentiviral vector, harvesting the cells a few days later, and isolating genomic DNA. This DNA is then used as a template to amplify a portion of the expected lentiviral insert.

Gene Name	PAH phenylalanine hydroxylase [ Homo sapiens ]
Gene Symbol	PAH
Synonyms	PH; PKU; PKU1
Gene Description	phenylalanine hydroxylase
GeneID	5053
Uni ProtID	P00439
mRNA Refseq	NM_000277.1
Protein Refseq	NP_000268.1
Chromosome Location	12q22-q24.2
Function	amino acid binding; cofactor binding; iron ion binding; phenylalanine 4-monooxygenase activity; protein homodimerization activity;
Pathway	Abnormal metabolism in phenylketonuria, organism-specific biosystem; Biogenic Amine Synthesis, organism-specific biosystem; Disease, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of amino acids and derivatives, organism-specific biosystem; Phenylalanine and tyrosine catabolism, organism-specific biosystem; Phenylalanine metabolism, organism-specific biosystem;
MIM	612349

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