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Panoply™ Human PAH Knockdown Stable Cell Line

Cat.No.
CSC-DC011255
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
PAH
Synonyms
PH; PKU; PKU1
Gene Description
phenylalanine hydroxylase
Gene ID
UniProt ID
P00439
mRNA Refseq
Protein Refseq
Chromosome Location
12q22-q24.2
Function
amino acid binding; cofactor binding; iron ion binding; phenylalanine 4-monooxygenase activity; protein homodimerization activity;
Pathway
Abnormal metabolism in phenylketonuria, organism-specific biosystem; Biogenic Amine Synthesis, organism-specific biosystem; Disease, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of amino acids and derivatives, organism-specific biosystem; Phenylalanine and tyrosine catabolism, organism-specific biosystem; Phenylalanine metabolism, organism-specific biosystem;
MIM

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