Rat Med1 cDNA Clone(NM_001134361.1)

Name: Rat Med1 cDNA Clone(NM_001134361.1)
SKU: CDFR009400
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR009400

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Product Information

Gene Information

Cat. No.	CDFR009400
Description	NativeORF clone of Rattus norvegicus mediator complex subunit 1 (Med1) as transfection-ready DNA NM_001134361.1
Product Type	cDAN Clone
Gene Abbr	Med1
Species	Rat
Vector	pCMV6Entry

Target Gene

MED1

Background

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. It also regulates p53-dependent apoptosis and it is essential for adipogenesis. This protein is known to have the ability to self-oligomerize. [provided by RefSeq, Jul 2008]

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