Human MED1 ORF clone(NM_004774.3)

Name: Human MED1 ORF clone(NM_004774.3)
SKU: CDCL185312
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCL185312

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Product Information

Gene Information

Cat. No.	CDCL185312
Description	ORF Clone of Homo sapiens mediator complex subunit 1 DNA.
Product Type	ORF clone
Gene Abbr	MED1
Species	Human
ORF Size	4746bp
Vector	pGEM-T
Warning	This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Storage	store at -20°C

Target Gene

MED1

Background

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. It also regulates p53-dependent apoptosis and it is essential for adipogenesis. This protein is known to have the ability to self-oligomerize. [provided by RefSeq, Jul 2008]

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