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Panoply™ Human WRN Knockdown Stable Cell Line

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Cat.No.
CSC-DC017533
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Gene
WRN
Gene Species
Human
Host Cell
HEK293 (Hela and other cell types are also available)
Growth Properties
Adherent
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Size
2 × 10^6 cells / vial
Storage
Liquid Nitrogen
Ship
Dry Ice
Gene Information
Official Symbol
WRN
Synonyms
RECQ3; RECQL2; RECQL3
GeneID
mRNA Refseq
Protein Refseq
MIM
UniProt ID
Q14191
Chromosome Location
8p12
Pathway
Integrated Pancreatic Cancer Pathway, organism-specific biosystem; Regulation of Telomerase, organism-specific biosystem;
Function
3-5 DNA helicase activity; 3-5 exonuclease activity; ATP binding; ATP-dependent 3-5 DNA helicase activity; ATP-dependent DNA helicase activity; ATPase activity; DNA binding; DNA helicase activity; DNA helicase activity; G-quadruplex DNA binding; Y-form DNA binding; bubble DNA binding; exonuclease activity; four-way junction helicase activity; helicase activity; magnesium ion binding; manganese ion binding; protein binding; protein complex binding; protein homodimerization activity;

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