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Panoply™ Human WRN Knockdown Stable Cell Line

Cat.No.
CSC-DC017533
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
WRN
Synonyms
RECQ3; RECQL2; RECQL3
Gene ID
UniProt ID
Q14191
mRNA Refseq
Protein Refseq
Chromosome Location
8p12
Function
3-5 DNA helicase activity; 3-5 exonuclease activity; ATP binding; ATP-dependent 3-5 DNA helicase activity; ATP-dependent DNA helicase activity; ATPase activity; DNA binding; DNA helicase activity; DNA helicase activity; G-quadruplex DNA binding; Y-form DNA binding; bubble DNA binding; exonuclease activity; four-way junction helicase activity; helicase activity; magnesium ion binding; manganese ion binding; protein binding; protein complex binding; protein homodimerization activity;
Pathway
Integrated Pancreatic Cancer Pathway, organism-specific biosystem; Regulation of Telomerase, organism-specific biosystem;
MIM

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