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Panoply™ Human LRP6 Knockdown Stable Cell Line

Cat.No.
CSC-DC008863
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
LRP6
Synonyms
LRP6; low density lipoprotein receptor-related protein 6; low-density lipoprotein receptor-related protein 6; LRP-6; ADCAD2; FLJ90062; FLJ90421;
Gene ID
UniProt ID
O75581
mRNA Refseq
BC117136
Chromosome Location
12p13.2
Function
Wnt-activated receptor activity; Wnt-protein binding; apolipoprotein binding; coreceptor activity involved in Wnt receptor signaling pathway; frizzled binding; kinase inhibitor activity; low-density lipoprotein receptor activity; protein binding; protein homodimerization activity; receptor acti
Pathway
Canonical Wnt signaling pathway, organism-specific biosystem; MicroRNAs in cardiomyocyte hypertrophy, organism-specific biosystem; Presenilin action in Notch and Wnt signaling, organism-specific biosystem; Wnt Signaling Pathway NetPath, organism-specific biosystem; Wnt Signaling Pathway and Pluripotency, organism-specific biosystem; Wnt signaling network, organism-specific biosystem; Wnt signaling pathway, organism-specific biosystem;
MIM

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