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LRP6


Official Full Name
LDL receptor related protein 6
Organism
Homo sapiens
Gene ID
4040
Background
This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.[provided by RefSeq, Dec 2009]
Synonyms
ADCAD2; STHAG7

Cat.No. Product Name Price
SHH334071 shRNA set against Human Lrp6 (NM_002336.2) Inquiry
SHH334075 shRNA set against Mouse Lrp6 (NM_008514.4) Inquiry
SHH334079 shRNA set against Rat Lrp6 (NM_001107892.1) Inquiry
SHW013059 shRNA set against Danio rerio LRP6 (NM_001134684) Inquiry
Cat.No. Product Name Price
CDCR374562 Rat Lrp6 ORF Clone(NM_001107892.1) Inquiry
CDFR007539 Rat Lrp6 cDNA Clone(NM_001107892.1) Inquiry
MiUTR1H-05901 LRP6 miRNA 3'UTR clone Inquiry
SKO0152 LRP6 Validated sgRNA vector Inquiry
CDCB174534 Danio rerio LRP6 ORF Clone (NM_001134684) Inquiry
CDCB186675 Rabbit LRP6 ORF clone (XM_002712655.2) Inquiry
CDCL128427 Human LRP6 ORF clone (NM_002336.2) Inquiry
CDCR245605 Mouse Lrp6 ORF Clone(NM_008514.4) Inquiry
CDCS410750 Human LRP6 ORF Clone (BC117136) Inquiry
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