Panoply™ Human DIO2 Over-expressing Stable Cell Line

Name: Panoply™ Human DIO2 Over-expressing Stable Cell Line
SKU: CSC-SC004309
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-SC004309

Host Cell : HEK293 (CHO and other cell types are also available) Size : >1x10⁶ frozen cells/vial

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Cell Line Information

Cell Culture Information

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Gene Information

Documents

Cat. No.	CSC-SC004309
Description	Using Creative Biogene's proprietary lentiviral vectors, we subclone the target gene into lentivector, generate the lentivirus particles, sequentially infect the cell line HEK293 (other cell types are also available according to your requirements), and select the clones constantly expressing target gene at high level.
Target Gene	DIO2
Gene Species	Homo sapiens (Human)
Host Cell	HEK293 (CHO and other cell types are also available)
Host Cell Species	Species varies
Applications	1. Gene expression studies 2. Signaling pathway research 3. Drug screening and toxicology 4. Disease research
Size	2 × 10^6 cells / vial
Stability	Validated for at least 10 passages
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid nitrogen
Shipping	Dry Ice

Revival

Rapidly thaw cells in a 37°C water bath. Transfer contents into a tube containing pre-warmed media. Centrifuge cells and seed into a 25 cm2 flask containing pre-warmed media.

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	DIO2 deiodinase, iodothyronine, type II [ Homo sapiens ]
Gene Symbol	DIO2
Synonyms	D2; 5DII; SelY; DIOII; TXDI2
Gene ID	1734
Uni Prot ID	A8K845
m RNA Refseq	NM_000793.5
Protein Refseq	NP_000784.2
Chromosome Location	14q24.2-q24.3
Function	selenium binding; thyroxine 5-deiodinase activity; thyroxine 5-deiodinase activity; ubiquitin protein ligase binding;
Pathway	Amine-derived hormones, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of amino acids and derivatives, organism-specific biosystem; Regulation of thyroid hormone activity, organism-specific biosystem; Selenium Metabolism and Selenoproteins, organism-specific biosystem; Selenium Pathway, organism-specific biosystem; Thyroxine biosynthesis, organism-specific biosystem;
MIM	601413

CSC-SC004309-Panoply™ Human DIO2 Over-expressing Stable Cell Line-Datasheet

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