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shRNA set against Rat DIO2 (NM_031720.3)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH278129

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Gene Information

Cat. No. SHH278129
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr DIO2
Gene Name Dio2 deiodinase, iodothyronine, type II [ Mus musculus ]
Species Rat
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name Dio2 deiodinase, iodothyronine, type II [ Mus musculus ]
Gene Symbol Dio2
Synonyms 5DII; DIOII; AI324267
Gene Description deiodinase, iodothyronine, type II
Gene ID 13371
Uni Prot ID Q9Z1Y9
m RNA Refseq NM_010050.2
Protein Refseq NP_034180.1
Chromosome Location 12 D3; 12
Function oxidoreductase activity; thyroxine 5-deiodinase activity; thyroxine 5-deiodinase activity; thyroxine 5-deiodinase activity; ubiquitin protein ligase binding;
Pathway Amine-derived hormones, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of amino acids and derivatives, organism-specific biosystem; Regulation of thyroid hormone activity, organism-specific biosystem; Selenium metabolism/Selenoproteins, organism-specific biosystem; Thyroxine biosynthesis, organism-specific biosystem; thyroid hormone metabolism I (via deiodination), organism-specific biosystem;
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