Panoply™ Human BDKRB2 Knockdown Stable Cell Line

Name: Panoply™ Human BDKRB2 Knockdown Stable Cell Line
SKU: CSC-DC001399
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC001399

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC001399
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	BDKRB2
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	BDKRB2 bradykinin receptor B2 [ Homo sapiens ]
Gene Symbol	BDKRB2
Synonyms	B2R; BK2; BK-2; BKR2; BRB2
Gene Description	bradykinin receptor B2
GeneID	624
Uni ProtID	P30411
mRNA Refseq	NM_000623.3
Protein Refseq	NP_000614.1
Chromosome Location	14q32.1-q32.2
Function	bradykinin receptor activity; phosphatidylinositol phospholipase C activity; protease binding; protein binding; protein heterodimerization activity; type 1 angiotensin receptor binding;
Pathway	ACE Inhibitor Pathway, organism-specific biosystem; Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Chagas disease (American trypanosomiasis), organism-specific biosystem; Chagas disease (American trypanosomiasis), conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem;
MIM	113503

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