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MLH1 miRNA 3'UTR clone

For research use only. Not intended for any clinical use.

Cat. No. :   MiUTR3H-00504

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Gene Information

Cat. No. MiUTR3H-00504
Description 3'UTR clone of mutL homolog 1 colon cancer nonpolyposis type 2 (E. coli) (MLH1) for miRNA target validation
Gene Abbr MLH1
Gene Name MLH1 mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) [ Homo sapiens ]
Species Human
Reporter luciferase-RFP
Promoter SV40
Resistance Neo/Kanr
Selection Marker Neomycin
Size The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials.
Vector pMirTarget
Vector Type plasmid
Storage -20 ℃
Gene Name MLH1 mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) [ Homo sapiens ]
Gene Symbol MLH1
Synonyms MLH1; mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli); COCA2, mutL (E. coli) homolog 1 (colon cancer, nonpolyposis type 2); DNA mismatch repair protein Mlh1; FCC2; HNPCC; HNPCC2; COCA2; hMLH1; MGC5172;
Gene ID 4292
Uni Prot ID P40692
m RNA Refseq BC006850
Chromosome Location 3p22.3
Function ATP binding; ATPase activity; contributes_to MutSalpha complex binding; guanine/thymine mispair binding; mismatched DNA binding; protein binding; contributes_to protein binding; contributes_to single-stranded DNA binding;
Pathway BRCA1-associated genome surveillance complex (BASC), organism-specific biosystem; Colorectal cancer, organism-specific biosystem; Colorectal cancer, conserved biosystem; Direct p53 effectors, organism-specific biosystem; Endometrial cancer, organism-specific biosystem; Endometrial cancer, conserved biosystem; Fanconi anemia pathway, organism-specific biosystem;
MIM 120436
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