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Human SCNN1A/SCNN1B/SCNN1G Stable Cell Line-CHO

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Cat.No.
CSC-RI0086
Background
The human SCNN1A, B and G genes encode the heteromeric ENaC channel, a constitutively active, amiloride-sensitive Na+-selective ion channel. ENaC expressed in kidney and colon is a therapeutic target in hypertension, congestive heart disease and inflammatory bowel disease.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
SCNN1G
Synonyms
SCNN1G; sodium channel, non-voltage-gated 1, gamma subunit; sodium channel, non voltage gated 1, gamma , sodium channel, nonvoltage gated 1, gamma; amiloride-sensitive sodium channel subunit gamma; ENaCgamma; SCNEG; gamma-ENaC; gamma-NaCH; ENaC gamma subunit; epithelial Na(+) channel subunit gamma; sodium channel, nonvoltage-gated 1, gamma; nonvoltage-gated sodium channel 1 subunit gamma; amiloride-sensitive sodium channel gamma-subunit; amiloride-sensitive epithelial sodium channel gamma subunit; PHA1; BESC3; ENaCg;
Gene ID
MIM
UniProt ID
P51170
Chromosome Location
16p12
Pathway
Aldosterone-regulated sodium reabsorption, organism-specific biosystem; Aldosterone-regulated sodium reabsorption, conserved biosystem; Taste transduction, organism-specific biosystem; Taste transduction, conserved biosystem;
Function
WW domain binding; ion channel activity; ligand-gated sodium channel activity; protein binding; sodium channel activity;

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