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Human GABRA2/GABRB3/GABRG2 Stable Cell Line-HEK293

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Cat.No.
CSC-RI0095
Background
The human GABRA2, GABRB3, and GABRG2 genes encode a GABA-activated, chloride-selective channel. GABAA receptors expressed in neurons are sites of action for benzodiazepines, barbiturates, and neurosteroids; and therapeutic targets in treatment of several neurological disorders including seizures, anxiety, and insomnia.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
HEK293
Ship
Dry ice
Gene Information
Official Symbol
GABRG2
Synonyms
GABRG2; gamma-aminobutyric acid (GABA) A receptor, gamma 2; gamma-aminobutyric acid receptor subunit gamma-2; GABA(A) receptor; gamma 2; GABA(A) receptor, gamma 2; GABA(A) receptor subunit gamma-2; CAE2; ECA2; GEFSP3;
Gene ID
MIM
UniProt ID
P18507
Chromosome Location
5q34
Pathway
GABA A receptor activation, organism-specific biosystem; GABA receptor activation, organism-specific biosystem; GABAergic synapse, organism-specific biosystem; GABAergic synapse, conserved biosystem; Ion channel transport, organism-specific biosystem; Ligand-gated ion channel transport, organism-specific biosystem; Morphine addiction, organism-specific biosystem;
Function
GABA-A receptor activity; benzodiazepine receptor activity; chloride channel activity; extracellular ligand-gated ion channel activity; ion channel activity; protein binding;

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